Understanding DNA - Edition 3 - By Chris R. Calladine, Horace Drew, Ben Luisi and Andrew Travers Elsevier Inspection Copies

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Understanding DNA,

Edition 3 The Molecule and How it Works

By Chris R. Calladine, Horace Drew, Ben Luisi and Andrew Travers

Publication Date: 13 Mar 2004

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Description

The functional properties of any molecule are directly related to, and affected by, its structure. This is especially true for DNA, the molecular that carries the code for all life on earth.

The third edition of Understanding DNA has been entirely revised and updated, and expanded to cover new advances in our understanding. It explains, step by step, how DNA forms specific structures, the nature of these structures and how they fundamentally affect the biological processes of transcription and replication.

Written in a clear, concise and lively fashion, Understanding DNA is essential reading for all molecular biology, biochemistry and genetics students, to newcomers to the field from other areas such as chemistry or physics, and even for seasoned researchers, who really want to understand DNA.

Key Features

Describes the basic units of DNA and how these form the double helix, and the various types of DNA double helix
Outlines the methods used to study DNA structure
Contains over 130 illustrations, some in full color, as well as exercises and further readings to stimulate student comprehension

About the author

By Chris R. Calladine, Dept. of Engineering, University of Cambridge, U.K.; Horace Drew, CSIRO Division of Biotechnology, Sydney, Australia; Ben Luisi, Department of Biochemistry, University of Cambridge, U.K. and Andrew Travers, MRC Laboratory of Molecular Biology, University of Cambridge, U.K.

Table of Contents

An Introduction to Molecular Biology for Non-Scientists
Why a Helix?
Different Kinds of Double Helix
Twisting and Curving
Curving in Three Dimensions
DNA Supercoiling
The Assembly of DNA intor Chromosomes
Specific DNA-Protein Interactions
Methods Used to Study the Structure of DNA
DNA in Disease, Diagnostics and Medicine
Cytosine Methylation and DNA Epigenetics

Appendix
1: Notes on the Derivation of Some Technical Terms
2: The Chemical Theory of Base-stacking Interactions in DNA
3: How to modify Gene Expression by means of Anti-sense Oligonucleotides, Ribozymes or si-RNA

Book details

ISBN: 9780121550899

Page Count: 352

Retail Price : £56.99

Calladine:UNDERSTANDING DNA, 2E (1997, 50.95 USD/ 34.95 GBP, ISBN: 0121550885)

Wolffe:CHROMATIN, 3E (1999, 41.95 USD/ 28.95 GBP, ISBN: 0127619151)

Audience

Advanced undergraduate and graduate students in molecular biology, biochemistry, and biophysics. Also of interest to researchers in related areas seeking a background to molecular biology

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