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The Human Genome,

Edition 2 A User's Guide

Editors: By Julia E. Richards and R. Scott Hawley

Publication Date: 07 Oct 2004

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This second edition of a very successful text reflects the tremendous pace of human genetics research and the demands that it places on society to understand and absorb its basic implications. The human genome has now been officially mapped and the cloning of animals is becoming a commonplace scientific discussion on the evening news. Join authors Julia Richards and Scott Hawley as they examine the biological foundations of humanity, looking at the science behind the sensation and the current and potential impact of the study of the genome on our society. The Human Genome, Second Edition is ideal for students and non-professionals, but will also serve as a fitting guide for the novice geneticist by providing a scientific, humanistic, and ethical frame of reference for a more detailed study of genetics.

Key Features

New in this edition:· 60% new material, including data from the Human Genome Project and the latest genetics and ethics discussions · Several new case studies and personal stories that bring the concepts of genetics and heredity to life· Simplified treatment of material for non-biology majors· New full-color art throughout the text· New co-author, Julia Richards, joins R. Scott Hawley in this revision

About the author

By Julia E. Richards, Professor of Ophthalmology and Visual Sciences and Professor of Epidemiology at the University of Michigan in Ann Arbor and R. Scott Hawley, American Cancer Society Research Professor and Investigator at the Stowers Institute for Medical Research

AcknowledgmentsPrefaceSECTION 1: The Basics of Heredity1. Slaying Molecular Dragons: Brenda’s Tale2. The Answer in a Nutshell: Genes, Proteins, and the Basis of Life3. Mendel and the Concept of the Gene4. Human Mendelian Genetics5. One Man’s Trait Is Another Man’s DiseaseSECTION 2: The Central Dogma of Molecular Biology6. DNA: The Genetic Alphabet7. The Central Dogma of Molecular Biology: How Genes Encode Proteins8. Splicing the Modular Gene9. Orchestrating the Human GenomeSECTION 3: How Chromosomes Move10. So What are Chromosomes Anyway?11. How Cells Move Your Genes Around12. Passing Genes Between Generations13. The Chromosomal Basis of HereditySECTION 4: Mutation14. Absent Essentials and Monkey Wrenches15. How We Detect Mutations16. We Are All Mutants17. What Constitutes Normal?18. Mutations in Mammoth Genes19. Expanded Repeat TraitsSECTION 5: Genes, Chromosomes, and Sex20. The X and Y Chromosomes: The Odd Couple21. Genetics of Sex, Gender, and Orientation22. Aneuploidy: When Too Much or Too Little CountsSECTION 6: Breaking the Rules23. Imprinting24. Imitating Heredity: One Trait, Many CausesSECTION 7: The Human Genome Landscape25. The Human Genome Project26. There’s Cloning and Then There’s Cloning27. The Human Genome Sequence28. Finding Genes in the Human GenomeSECTION 8: Complex and Heterogeneous Traits29. Genotype Phenotype Correlations30. How Complex Can It Get?31. Quantitative Traits32. The MAOA Gene: Is There a Genetic Basis for Criminality?33. The Multiple-Hit Hypothesis: The Genetics of CancerSECTION 9: Genetic Testing and Therapy34. Genetic Testing and Screening35. Magic Bullets: The Potential for Gene TherapySECTION 10: Fears, Faith, and Fantasies36. Heroes Among Us37. Fears, Faith, and FantasiesCreditsIndex

ISBN: 9780123334626

Page Count: 480

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Professionals and educated laypersons studying the impact of genetics, medicine, and society; and non-biology majors in courses such as Genetics in Society.

The Human Genome,

Editors: By Julia E. Richards and R. Scott Hawley

Key Features

About the author

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