Fundamentals of Forensic DNA Typing,
Edition 1
By John M. Butler

Publication Date: 20 Aug 2009
Description
Fundamentals of Forensic DNA Typing is written with a broad viewpoint. It examines the methods of current forensic DNA typing, focusing on short tandem repeats (STRs). It encompasses current forensic DNA analysis methods, as well as biology, technology and genetic interpretation. This book reviews the methods of forensic DNA testing used in the first two decades since early 1980’s, and it offers perspectives on future trends in this field, including new genetic markers and new technologies. Furthermore, it explains the process of DNA testing from collection of samples through DNA extraction, DNA quantitation, DNA amplification, and statistical interpretation. The book also discusses DNA databases, which play an important role in law enforcement investigations. In addition, there is a discussion about ethical concerns in retaining DNA profiles and the issues involved when people use a database to search for close relatives. Students of forensic DNA analysis, forensic scientists, and members of the law enforcement and legal professions who want to know more about STR typing will find this book invaluable.

Key Features

  • Includes a glossary with over 400 terms for quick reference of unfamiliar terms as well as an acronym guide to decipher the DNA dialect
  • Continues in the style of Forensic DNA Typing, 2e, with high-profile cases addressed in D.N.A.Boxes-- "Data, Notes & Applications" sections throughout
  • Ancillaries include: instructor manual Web site, with tailored set of 1000+ PowerPoint slides (including figures), links to online training websites and a test bank with key
About the author
By John M. Butler, NIST Fellow and Special Assistant to the Director for Forensic Science, Office of Special Programs, at the U.S. National Institute of Standards and Technology, in Gaithersburg, Maryland.
Table of Contents
Foreword
Introduction
Acknowledgments
About the Author

1 Overview and History of DNA Typing
2 Basics of DNA Biology and Genetics
3 Historical Methods
4 Sample Collection, Storage, and Characterization
5 DNA Extraction
6 DNA Quantitation
7 DNA Amplification (The Polymerase Chain Reaction)
8 Short Tandem Repeat Markers
9 Fundamentals of DNA Separation and Detection
10 STR Genotyping and Data Interpretation
11 Statistical Interpretation: Evaluating the Strength of Forensic DNA Evidence
12 DNA Databases
13 Quality Assurance
14 Forensic Challenges: Degraded DNA, Mixtures, and LCN
15 Additional Loci and Nonhuman DNA Testing
16 Lineage Markers: Y Chromosome and mtDNA Testing
17 Applications of DNA Typing
18 Future Trends

Appendix
1 Glossary of Terms
2 Useful Web Sites
3 Probability and Statistics
Index

References are provided at the end of each chapter by subtopic (but without direct citation within the text).

High-profile cases and other interesting information are included as D.N.A. (Data, Notes, and Applications) boxes scattered throughout the book in the chapter pertaining to a particular subject.
Book details
ISBN: 9780123749994
Page Count: 520
Retail Price : £39.99
9781420063295; 9780791089231; 9780470010259
Audience
Undergraduate forensic science students, lawyers who need enough cursory information to understand and speak to jury, law enforcement, crime scene investigators, legal professionals and government/legal policy makers