Risk Factors for Psychosis: Paradigms, Mechanisms, and Prevention combines the related, but disparate research endeavors into a single text that considers all risk factors for psychosis, including biological, psychological and environmental factors. The book also introduces the ethics and current treatment evidence that attempts to ameliorate risk or reduce the number of individuals with risk factors developing a psychotic disorder. Finally, the book highlights new research paradigms that will further enhance the field in the future.
Psychotic disorders affect more than 50 million people worldwide, creating a devastating effect on lives and causing major financial and emotional impact on families and on society as a whole. The search for risk factors for psychosis has developed rapidly over the past decades, invigorated by changes in the thinking about the malleability and treatability of psychotic disorders. The paradigms for investigating psychosis risk have developed, often in parallel, but there has been no book to date that has summarized and synthesized the current approaches.
Key Features
- Integrates research from biological, psychological and environmental factors into a single resource
- Offers insight into at-risk paradigms, biomarkers, and the current state of research on treatment option for psychosis
- Presents a holistic and dynamic look at risk syndromes and how they can be measured through neuroimaging, neuropsychology and other methods
CRISTINA MEI AND PATRICK D. MCGORRY
2. Principles of risk, screening, and prevention in psychiatry
EMMA SONESON, JESUS PEREZ, AND PETER B. JONES
I - Risk paradigms
3. At-risk mental states
ALISON R. YUNG
4. Subjective disturbances in emerging psychosis: basic symptoms and self-disturbances
FRAUKE SCHULTZE-LUTTER, CHANTAL MICHEL, RAHEL FL €UCKIGER, AND ANASTASIA THEODORIDOU
5. Schizotypy, schizotypal personality, and psychosis risk
NEUS BARRANTES-VIDAL, ANNA RACIOPPI, AND THOMAS R. KWAPIL
6. Familial high risk and high-risk studies
LIANA ROMANIUK, STELLA W.Y. CHAN, ALIX MACDONALD, JESSIKA E. SUSSMANN, ANDREW M. MCINTOSH, HEATHER C. WHALLEY, AND STEPHEN M. LAWRIE
7. Psychotic-like experiences in the general population
COLM HEALY AND MARY CANNON
8. 22q11.2 deletion syndrome: a neurodevelopmental model of psychosis
CORRADO SANDINI, STEPHAN ELIEZ, MAUDE SCHNEIDER, AND MARCO ARMANDO
II - Specific areas and risk
9. Neuroimaging studies in people at clinical high risk for psychosis
GEORGE GIFFORD, ROB MCCUTCHEON, AND PHILIP MCGUIRE
10. Genetic studies of psychosis
HANNAH J. JONES, STANLEY ZAMMIT, AND JAMES T.R. WALTERS
11. Immune processes and risk of psychosis
ADAM AL-DIWANI AND THOMAS ARTHUR NICHOLLS POLLAK
12. Neurochemical models of psychosis risk and onset
DOMINIC OLIVER, GEMMA MODINOS, AND PHILIP MCGUIRE
13. Clinical risk factors for psychosis
ASWIN RATHEESH, JESSICA A. HARTMANN, AND BARNABY NELSON
14. Cognitive risk factors for psychosis
KELLY ALLOTT AND ASHLEIGH LIN
15. Society and risk of psychosis
CRAIG MORGAN, TESSA ROBERTS, BRIAN O. DONOGHUE, AND ANDREW THOMPSON
16. Is there sufficient evidence that cannabis use is a risk factor for psychosis?
MARCO COLIZZI AND SAGNIK BHATTACHARYYA
III - Interventions
17. The ethics of identifying and treating psychosis risk
PAOLO CORSICO AND ILINA SINGH
JEAN ADDINGTON, DANIJELA PISKULIC, DANIEL J. DEVOE, OLGA SANTESTEBAN-ECHARRI, AND JACQUELINE STOWKOWY
19. Pharmacological intervention for people at risk of psychotic disorder
E. BURKHARDT, K. LEOPOLD AND A. BECHDOLF
20. International services for assessing and treating psychosis risk
CHRISTY L.M. HUI, W.C. CHANG, SHERRY K.W. CHAN, EDWIN H.M. LEE, Y.N. SUEN, AND ERIC Y.H. CHEN
21. New paradigms to study psychosis risk: clinical staging, pluripotency, and dynamic prediction
RACHAEL SPOONER, JESSICA A. HARTMANN, PATRICK D. MCGORRY, AND BARNABY NELSON
22. Future directions in risk research
NIKOLAI ALBERT, LOUISE BIRKEDAL GLENTHØJ, AND MERETE NORDENTOFT
9780128018293; 9780128009819; 9780444520029
