Key Features
- Offers comprehensive coverage of a broad range of topics related to dementia
- Serves as a foundational collection for neuroscientists and neurologists on the biology of dementia and brain dysfunction
- Contains in each chapter an abstract, key facts, mini dictionary of terms, and summary points to aid in understanding
- Provides unique sections on specific subareas, intellectual components, and knowledge-based niches that will help readers navigate key areas for research and further clinical recommendations
- Features preclinical and clinical studies to help researchers map out key areas for research and further clinical recommendations
- Serves as a "one-stop" source for everything you need to know about dementia
Part I: Dementia: introductory chapters and setting the scene
1. Mixed dementia: a neuropathological overviewJacques De Reuck
2. Vascular dementia: an overviewVirginia Cipollini, Fernanda Troili and Franco Giubilei
3. Small vessel disease and dementiaFrancesco Arba and Valentina Rinnoci
4. Linking amyotrophic lateral sclerosis and frontotemporal dementiaCouratier Philippe
5. Mortality in dementia: linking in the role of deliriumFlavia Barreto Garcez and Thiago Junqueira Avelino-Silva
6. Midlife diabetes and the risk of dementia: understanding the linkAdam H. Dyer and Sean P. Kennelly
7. Gait and dementiaOshadi Jayakody and Michele L. Callisaya
8. The role of blood pressure and hypertension in dementiaKeenan A. Walker and Rebecca F. Gottesman
9. Genetics of dementia: a focus on Alzheimer’s diseaseFrancesca Fernandez and Jessica L. Andrews
10. Clinical and pathological phenotypes in dementia: a focus on autosomal dominant frontotemporal dementiaInnocenzo Rainero, Alessandro Vacca and Elisa Rubino
11. Environmental and genetic risk factors for dementiaVanesa Bellou, Lazaros Belbasis and Evangelos Evangelou
12. Lipids, brain ageing, dementia, and lipidomicsAnne Poljak, Braidy Nady, Wong Matthew Wai Kin, Yue Liu, Mahboobeh Housseini and Sachdev Perminder Singh
13. The 5xFAD mouse model of Alzheimer’s disease Caroline Ismeurt, Patrizia Giannoni and Sylvie Claeysen
Part II: Biomarkers, psychometric instruments and diagnosis
14. Use of cerebrospinal fluid in diagnosis of dementiaAngelo Nuti, Cecilia Carlesi, Elena Caldarazzo Ienco, Gabriele Cipriani and Paolo Del Dotto
15. Salivary biomarkers in Alzheimer’s disease Jessica L. Andrews and Francesca Fernandez
16. Diacylglycerols: biomarkers of a sustained immune response in proteinopathiesPaul L. Wood and Randall J. Woltjer
17. Butyrylcholinesterase as a biomarker in Alzheimer’s diseaseDrew R. DeBay and Sultan Darvesh
18. Blood brain-derived neurotrophic factor as a biomarker of Alzheimer’s diseaseMarta Balietti
19. The neuroscience of dementia: diagnosis and management methods of amyloid positron emission tomography imaging and its application to the Alzheimer’s disease spectrumShizuo Hatashita
20. Diffusion-weighted imaging (DWI) tractography and Alzheimer’s diseaseNicola Amoroso
21. Transcranial magnetic stimulation in the cortical exploration of dementiaThanuja Dharmadasa, William Huynh and Matthew C. Kiernan
22. The role of retinal imaging in Alzheimer’s diseaseVictor T.T. Chan and Carol Y. Cheung
23. Prediction of Alzheimer’s diseaseAthanasios Alexiou, Stylianos Chatzichronis and Ghulam Md Ashraf
24. Addenbrooke’s Cognitive ExaminationJordi A. Matias-Guiu
25. Beyond the cutoffs: a Bayesian approach to the use of the Montreal Cognitive Assessment as a screening tool for mild cognitive impairment and dementiaAndrea Bosco, Alessandro O. Caffo, Giuseppina Spano and Antonella Lopez
26. Utility of ALBA screening instrument: the prodromal phase of dementia with Lewy bodiesWaleska Berríos and Angel Golimstok
27. The quick mild cognitive impairment screen and applications to dementia Ron an O’Caoimh, D. William Molloy and Roger Clarnette
28. The usefulness of evaluating performance of activities of daily living in the diagnosis of mild cognitive disordersPatricia De Vriendt, Elise Cornelis and Ellen Gorus
Part III: Pharmacological treatments for dementia
29. Cholinesterase inhibitors in dementias: an overviewPatrizia Mecocci, Lucia Paolacci and Virginia Boccardi
30. Choline-containing phospholipids and treatment of adult-onset dementia disordersFrancesco Amenta, Gopi Battineni, Enea Traini and Graziano Pallotta
31. Donepezil in the treatment of Alzheimer’s diseaseGabriella Marucci, Michele Moruzzi and Francesco Amenta
32. Memantine and Alzheimer’s disease: a comprehensive reviewSergio del Río-Sancho
33. A new neuroprotective strategy for the drug therapy of Parkinson’s disease: the Ca2þ/cAMP signaling as therapeutic targetAfonso Caricati-Neto, Fulvio Alexandre Scorza and Leandro Bueno Bergantin
34. Pitfalls and possible solutions for research and development of dementia therapiesThomas Muller €
35. All-trans retinoic acid in Alzheimer’s diseaseSiamak Beheshti
36. Dementia and usage of N-methyl-D-aspartate receptor antagonistsB.E. Glynn-Servedio
37. Swallowing impairment in Parkinson’s diseaseMaira Rozenfeld Olchik, Marina Padovani and Annelise Ayres
38. Linking astrocytes’ exosomes to Alzheimer pathogenesis and therapyAnna M. Chiarini, Ubaldo Armato, Claudio Eccher and Ilaria Dal Pr
39. Changing fate: therapeutic mechanisms focused on the switch of amyloid precursor protein processingSven Reinhardt and Kristina Endres
40. Acetylcholinesterase inhibitory agents in plants and their application to dementia: Alzheimer’s diseaseWillian Orlando Castillo-Ordonez and Nohelia Cajas-Salazar
41. Removal of blood amyloid-b as an effective and safe therapeutic strategyNobuya Kitaguchi, Kazunori Kawaguchi and Kazuyoshi Sakai
Part IV: Non-pharmacological treatments and procedures
42. Caring for people with dementia in the acute hospitalRobert Briggs, Paul Claffey and Sean P. Kennelly
43. Environmental enrichment as a preventative and therapeutic approach to Alzheimer’s diseaseKimberley E. Stuart, Anna E. King and James C. Vickers
44. Music therapy in dementia: the effects of music therapy and other musical interventions on behavior, emotion, and cognitionAlfredo Raglio and Lapo Attardo
45. Exploitation of aromatherapy in dementiadimpact on pain and neuropsychiatric symptomsDamiana Scuteri, Laura Rombol
46. Dancing in dementiaLee-Fay Low, Helen Parker, Kathryn Dovey and Alycia Fong Yan
47. Hypoxicehyperoxic conditioning and dementiaRobert T. Mallet, Johannes Burtscher, Eugenia B. Manukhina, H. Fred Downey, Oleg S. Glazachev, Tatiana V. Serebrovskaya and Martin Burtscher
48. Linking amyloid and depression in the development of Alzheimer’s disease: effects of neuromodulatory interventions by brain stimulationAkihiko Nunomura, Toshio Tamaoki, Kenji Tagai, Shinsuke Kito, Shunichiro Shinagawa and Masahiro Shigeta
49. Regional and local dementia care networksFranziska Laporte Uribe, Karin Wolf-Ostermann, Jochen Rene Thyrian and Bernhard Holle
50. Cognitive behavioral therapy use in Alzheimer’s disease: mitigating risks associated with the olfactory brainLarry D. Reid, Dylan Z. Taylor and Alicia A. Walf
51. Maximizing cognition in mild cognitive impairment and early stage dementiaBridget Regan, Yvonne Wells and Paul O’Halloran
52. Exercise, cognitive creativity, and dementiaEmily Frith and Paul D. Loprinzi
53. Person-centered communication among formal caregivers of persons with dementiaMarie Y. Savundranayagam and Pabiththa Kamalraj
Index
Rosenberg & Pascual