Biological Inorganic Chemistry,
Edition 1
An Introduction
Editors:
By Robert R. Crichton
Publication Date:
11 Dec 2007
The importance of metals in biology, the environment and medicine has become increasingly evident over the last twenty five years. The study of the multiple roles of metal ions in biological systems, the rapidly expanding interface between inorganic chemistry and biology constitutes the subject called Biological Inorganic Chemistry. The present text, written by a biochemist, with a long career experience in the field (particularly iron and copper) presents an introduction to this exciting and dynamic field. The book begins with introductory chapters, which together constitute an overview of the concepts, both chemical and biological, which are required to equip the reader for the detailed analysis which follows. Pathways of metal assimilation, storage and transport, as well as metal homeostasis are dealt with next. Thereafter, individual chapters discuss the roles of sodium and potassium, magnesium, calcium, zinc, iron, copper, nickel and cobalt, manganese, and finally molybdenum, vanadium, tungsten and chromium. The final three chapters provide a tantalising view of the roles of metals in brain function, biomineralization and a brief illustration of their importance in both medicine and the environment.
Key Features
Relaxed and agreeable writing style. The reader will not only fiind the book easy to read, the fascinating anecdotes and footnotes will give him pegs to hang important ideas on.Written by a biochemist. Will enable the reader to more readily grasp the biological and clinical relevance of the subject.Many colour illustrations. Enables easier visualization of molecular mechanismsWritten by a single author. Ensures homgeneity of style and effective cross referencing between chaptersPart 1 Basic Principles
- An overview of metals in biology
- Basic coordination chemistry for biologists
- Biological ligands for metal ions
- Structural and molecular biology for chemists
- An overview of intermediary metabolism and bioenergetics
- Methods which can be used to study metals in biology
- Metal assimilation pathways
- Transport, storage and homeostasis of metal ions
- Sodium and potassium
- Magnesium
- Calcium
- Zinc
- Iron
- Copper
- Nickel and cobalt
- Manganese
- Molybdenum, vanadium, tungsten and chromium
- Non-metals in biology
- Biomineralisation
- Metals in brain function
- Metals and neurodegeneration
- Metals in medicine and metals as drugs
- Metals in the environment and metal toxicity
Part 2 Metals in Biology
Part 3 Metals in Medicine and the environment
ISBN:
9780444527400
Page Count: 381
Retail Price
:
£61.99
Student: Chemists / biologists following courses in Inorganic biochemistry / Bioinorganic chemistry. Chemistry, biology, medicine, environmental sciencesResearcher: Because it is clearly written and gives a homogeneous view of the subject Chemistry, biology, microbiology, plant science, medical research (preclinical and clinical) environmental researchConsultant: To have access to important informations collected in one volume. Pharmacological industry, foodstuffs and agro-industries, environmental applications
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